Physical development of children with congenital syphilis
The study of the indices of the physical development of the children of the first three years of life with diagnosed congenital syphilis made it possible to establish a reliable decrease in their growth-weight indices, both at birth and the first three years of life.
Decree of the Government of the Russian Federation from 1.12. 2004, syphilitic infection is included both as a socially significant disease and as a disease that poses a danger to others.
Currently, according to statistical services, there is a relative stabilization of the incidence of syphilis, but the problem remains acute-social. According to the Federal Center for Hygiene and Epidemiology (2007), about 50% of patients with syphilis constitute patients with syphilis pregnant women, and in 85% of cases the early latent form of syphilis is diagnosed. Transmission of syphilitic infection to offspring is most likely in the first three years after infection of the mother.
With the passage of time, this ability decreases, but does not disappear completely. With early syphilis in a pregnant woman, the probability of infection of the fetus is 80%.
Infection with syphilis fetus occurs as a result of penetration through the placenta in the body of the child pale treponema. Pathological changes in the fetus occur at 20-22 weeks gestation, when placental circulation develops. Therefore, early diagnosis of syphilis and active treatment of this infection in the early stages of pregnancy enable the birth of healthy offspring. The pathogenesis of the congenital form of syphilis depends on the degree of infection of the fetus, the formation of an immune response by the fetus and directly damaging the action of pale treponema.