Parasitosis in children and allergic reactions associated with them
Every day almost every doctor consults and treats children with allergies. But not always an allergy can be associated with exposure from outside. There are situations when a child becomes a hostage of parasitic terror. Comfortably located inside the child’s body, the parasite breeds and grows, leaving the baby with only the products of its vital activity. But in case of individual intolerance helminths in children, there may be an allergic reaction of the body, manifested by increased body temperature, rash, etc. Often such an allergy is misunderstood by doctors, which leads to the appointment of inadequate treatment, and, as a result, the appearance of complications. So how do you recognize a parasitic allergy from a large number of other allergic species?
When the baby’s body is captured by parasites, it includes a specific immunological defense mechanism. The nature of protection always depends and is closely related to the variety of the parasite, the stage of its development, its location and the parasitic tactics of survival. Endogenous and exogenous metabolic products are the source of a large number of antigens. This is due to the complex structure of the parasite itself. And those reactions that arise in the child’s body, strongly depend on the antigenic variety of the invading helminth. The immune response of the body to penetration of the helminth is usually very weak and specific. Most parasites are localized in the intercellular space and, as a rule, they do not have the reproduction in the host’s body, which confirms the weak immunogenicity of the organism.
Some types of helminths penetrate into the muscle tissue, causing their destruction, and, as a consequence, myositis. After penetrating into the muscle tissue, a capsule forms around the parasite. These capsules are so reliable that they are able to protect the parasite even for several months after the death of the host. In some intestinal helminths, it is possible to cause an inflammatory reaction in the host in response to which their spontaneous excretion occurs.
These features include:
- Lack of phagocytosis;
- The appearance of antibody-dependent cell-mediated cytotoxicity (AZKTS);
- Development of allergic reactions:
- Generation of a Th2 response, production of IL-4, -5, -6, -9, -13 and eosinophils and IgE.
Proceeding from this, it can be said that most of the pathological reactions of the body are formed against the background of the development of immune reactions, including allergic manifestations. Some physicians believe that an increase in the number of allergic diseases is associated with an improvement in the epidemiological situation. Over the past 50 years or so, medicine has made great strides in the antibacterial treatment of tuberculosis, malaria, and so on, and the level of sanitary and hygienic conditions in the world has significantly increased. This is what led to a change in the bacterial-viral spectrum of the environment and the growth of allergic cases. Immunity has ceased to experience such large infectious and parasitic loads as before. The diet and microbiocinosis of the intestine, which affect the immune formation, also changed.
Hello. My name is Polina. Hearing once the truth that a pediatrician is the chief doctor for any family with young children, I realized that I have something to strive for.