Fever and the use of antipyretic drugs in children
The temperature of the human body in normal situations is strictly controlled by the nervous system in order to prevent pronounced shifts in metabolism. However, under extreme conditions, in order to accelerate the course of an unfavorable period, the body itself increases body temperature and enhances the course of metabolic processes, accelerates the response of vital activity. This process is called a fever.
There is a second option for increasing body temperature – this is overheating. Hyperthermia occurs as a result of disturbance of the mechanisms of thermoregulation and the predominance of heat production over heat transfer due to its insufficiency, resulting in an increase in body temperature. The causes of overheating can be either external (as a result of increased heat production under the influence of physical or chemical factors), and internal (for violations in the hypothalamus and problems associated with mitochondria cells). The formation of hyperthermia occurs without the participation of the immune system and can not proceed for a long time, since in the future irreversible changes occur in the form of denaturation of proteins and disturbance of homeostasis, resulting in the development of hemolysis, hemorrhagic syndrome, and death of neurons (with an increase in body temperature to 42oC). The lethal outcome occurs when the temperature is overheated to 43 ° C.
Hello. My name is Polina. Hearing once the truth that a pediatrician is the chief doctor for any family with young children, I realized that I have something to strive for.