Главная 7 Child development 7 Anti-Muller Hormone: a litmus test of women’s health

Anti-Muller Hormone: a litmus test of women’s health

Anti-Muller Hormone: a litmus test of women's health

Perhaps you have never heard of a hormone antimühler. what it is, young ECO-mothers are well aware of, since the test for AMH is one of the obligatory tests during the procedure of artificial insemination.

It is noteworthy that the hormone antimullers itself has no effect on the ability of a woman to conceive and endure a healthy baby. However, the level of AMH in the body very accurately predicts not only the chances of natural conception, but also the success of IVF. This is a kind of “litmus test” of female fertility and women’s health.

Antimulants hormone in women is a “by-product” of the ovaries. It is produced by the cells of the egg-containing follicles, but only during its maturation.

Therefore, according to the AMG level, it is possible to judge exactly how the ovaries work and how many eggs they contain that can “ripen” for fertilization. Depending on the age of the woman, the antimühler hormone has a different level. It cannot be determined in girls before puberty, that is, before the start of the first menstrual cycle.

It is zero in women who have gone out of childbearing age due to natural causes – during menopause. Maximum values ​​of AMG are normally fixed at the peak of female fertility – from 20 to 30 years. It has low values ​​in those women who have difficulty with natural conception.

The lower the level of anti-Muller hormone, the less likely a woman is to become pregnant.

In medicine, there is the term “ovarian reserve” – ​​this is the remaining number of eggs in a woman who can still ovulate and be fertilized. Why the “remaining”? Because each of us is born with an already fixed number of immature eggs contained in the so-called “primordial follicles.” The fate of future motherhood is decided on the third month of intrauterine development of the girl.

How many primordial follicles are formed during this period, so many eggs and will be in the arsenal of a woman when she comes to the childbearing age.

Before the start of the first menstrual cycle, these immature follicles are dormant. Then, normally, at intervals of about 28 days, one follicle matures (more rarely, several), giving birth to a mature, ready-to-fertilize egg.

Therefore, since the first menstruation, the number of fertilized eggs will only decrease. And what remains in the ovaries of a woman is her child-bearing “reserve”.

And this dynamic can be seen with the help of a test for anti-Muller hormone. Its level in an adult woman of childbearing age is currently the most accurate marker (that is, indicator) of a woman’s ovarian reserve.

In terms of AMG, it is possible to predict the time of menopause with very high accuracy, that is, the moment when a woman will no longer have eggs.

When performing artificial insemination procedures, the AMH test is used to assess the probability of pregnancy after ovarian stimulation. The level of anti-Mullerian hormone in this case will indicate whether such stimulation was successful, whether it will be possible to obtain a number of viable eggs that are sufficient for IVF, and even the probability of pregnancy in these conditions.

Anti-Muller Hormone: a litmus test of women's health

Diagnostic value is not only a reduced level of AMH. If the analysis shows that the hormone has increased antimullers, this may indicate certain ovarian dysfunctions.

For example, AMH is increased by 2-3 times in case of polycystic ovary syndrome, as well as in primary ovarian failure – a condition in which a woman has several eggs in one menstrual cycle, which leads to premature depletion of the ovarian reserve. Substantially elevated AMH may be a symptom of ovarian granulose cell tumors.

With a significant increase in the anti-Mullerian hormone in IVF patients during ovarian stimulation, doctors talk about an excessive response to ovarian stimulation (superovulation), when too many eggs begin to mature at the same time. In this case, the treatment of infertility is corrected before IVF.

In the diagnosis of ovarian reserve in women of reproductive age, it is considered to be the norm for fluctuations in the AMH level in the range from 0.2 to 11 ng / ml (according to other data, from 0.5 to 12.6 ng / ml). Data may vary in different laboratories. It should be borne in mind that experts should deal with the interpretation of the results of the test for antimullers hormone.

Referral to the analysis of AMH, as a rule, gives the endocrinologist. For analysis of antimullers, the hormone gives blood from a vein on an empty stomach.

An analysis of antimühler hormone for 3-5 days of the cycle. This is due to the fact that often patients are simultaneously prescribed a test for follicle-stimulating hormone (FSH) for a comprehensive assessment of ovarian function.

Otherwise, the day of the cycle does not play a special role.

In the middle of the 19th century, the German anatomist Johan Muller discovered that during the prenatal period, a duct develops in the embryo, which in girls precedes the uterus, fallopian tubes and upper third of the vagina. This duct was called – “Mullerov.”

It is noteworthy that at first it is in both boys and girls, but, as scientists of the 20th century have found out, later in the male embryo a substance begins to be produced, which leads to the resorption of this “female” Mullerian duct. Hence the name “antimuhler hormone.” Even later, it turned out that this substance in men is produced even after birth, in childhood, gradually fading away almost as an adult.

And in women, on the contrary, the first traces of the anti-Mullerian hormone can be seen only after the maturation of the first egg, that is, during the pubertal period.

О admin

x

Check Also

How to start trusting your husband again?

The physical closeness of this girl to your home reminds you of treason, of the ...

There is a contact

However, conversations with the stomach are not easily given to all parents – to some ...

Once again about love: the sexual life of pregnant

Within 9 months, the attitude of future parents to have sex will change, and this ...

We are going on vacation!

Be sure to discuss your vacation plans with your doctor. If there are any complications ...

Breastfeeding: the main thing – a good start

One of the main rules of success – the correct position of the mother and ...

If the track is long …

Do not rush to explore uncharted paths immediately after arriving at a new place. Let ...

Horoscope for November

In the 1st decade, young Aries are very serious about everything. From 10 to 24 ...

Technique for life

First of all, it is an important part of the world, because the Earth, the ...

Can a pregnant woman travel: where and when

Before going to a travel agency, the expectant mother should look into her doctor. It ...

How to equip a nursery for the future first graders

The age at which children enter first grade coincides with a transitional stage in the ...

Specialty Food

Functional nutrition (FP) – the so-called new chapter of our life – is made up ...

Lose weight in French: hips, legs, buttocks

Our buttocks, thighs, and legs are a whole thing! We always think that they are ...

Hormonal (genital) crisis in a newborn

The genital crisis of newborns is a unique way of adapting a baby to new ...

New Year’s story in “Masterslavl”: a marathon of good deeds!

This year, Masterslavl City Council continues the marathon of good deeds, and according to tradition, ...

Kids and soda

For the first time, sparkling water was obtained in England in the 18th century. Then ...

Homeopathy during pregnancy

Classical homeopathy appeared at the end of the 18th century thanks to the research of ...

Twins at Hollywood Stars

For the first time, Krutoy Walker married Diana Holechek in 1958, barely 18 years old, ...

Business style

Do a 15-minute warm-up every hour. Extend your legs more often under the table to ...

We quit the child from the first days

A huge number of bacteria, viruses and fungi enter our bodies. They are opposed to ...

A child has a cold: what and how to treat

A runny nose, or rhinitis, is not a disease, but a symptom of it. To ...

Women trying to lose weight should start to eat like a man

Referring to research conducted by the University of Toronto, White explains his rather provocative position ...

How to make him a massage?

In order for the massage to take place, first of all make contact with the ...

Mountains, air and Narzan: family rest and treatment in Kislovodsk

Zheleznovodsk specializes in diseases of the digestive system, kidney and urinary tract diseases, Pyatigorsk’s “trick” ...

Shopping for a newborn

This section is devoted to what items will help make the life of the child ...